The Ultimate Guide to the Top 10 Best Largo Combinations in Slime Rancher 2

As an avid Slime Rancher with over 100 hours played across both games, I‘ve created just about every largo combination imaginable. In this ultimate guide, I‘ll share my picks for the top 10 best largos in Slime Rancher 2 for a profitable ranch.

Largo slimes

What Are Largo Slimes?

For newcomers to the wacky world of Slime Rancher, a quick biology lesson. Largo slimes are formed when a pure slime consumes a plort (the collectible slime poop) that is not of its kind. For example, feeding a pink slime a rad plort will transform it into a pink rad largo.

These hybrids exhibit traits of both parent slimes. Largos are bigger, cannot be vac-packed, and cannot turn back into pure slimes once created. They produce 2-4 plorts at a time: one of each parent slime type.

So what makes an S-tier largo for advanced ranchers? Based on my experience, here are the key factors:

Diet and Needs – How easy or difficult is the largo to feed and keep happy?

Plort Profitability – How valuable are the two plort types produced? More newbucks = happier ranchers!

Ranching Difficulty – Are they challenging to contain or ranch efficiently?

Early-Game Availability – Can the component slimes be accessed early on?

With these criteria guiding my picks, let‘s count down the top 10 best largos in Slime Rancher 2!

#10 – Pink Rock Largo

Kicking off the list is the classic starter largo, the pink rock hybrid. Both pink and rock slimes appear very early on and enjoy the same diet of heart beets. By mixing them, you get a hardy and easygoing largo.

While their plorts only sell for 10-15 newbucks each, the pink rock largo is simple to feed. Their veggie diet means you can use garden farming to automate feeding. Heart beet, odd onion, silver parsnip – they devour it all!

Easy containment combined with decent plort volume makes the pink rock largo a great low-maintenance starter largo.

Diet: Veggies, especially Heart Beets
Plort Profit: 10-15 newbucks each (Low)
Ranching Difficulty: Very Easy

#9 – Tabby Phosphor Largo

This peppy hybrid merges the playful tabby with the illuminating phosphor slimes.

Phosphor plorts sell incredibly well at 25 newbucks each. However, pure phosphors require some management as they phase out in sunlight.

Tabbies offset this nuisance nicely with their very easygoing nature. Their plorts fetch 22 newbucks a piece, so respectable income too!

Feed your tabby phosphor largo meat or fruit and watch profits stack up nicely once you build some solar shade for them. Tabbies happily munch any food so maintaining their diet is simple compared to finicky slimes.

Just be sure to give them toys and scritches! As a tip – set up gardens, coops, or ponds near their corral for easy automation.

Diet: Meat & Fruit
Plort Profit: 44 newbucks for 2 (High)
Ranching Difficulty: Medium

#8 – Honey Boom Largo

The normally volatile boom slime becomes much easier to manage when hybridized with the laid-back honey slime.

Ranching honey boom largos removes the risk of rogue booms demolishing your ranch. Instead you get happy honey slime vibes keeping those booms relaxed.

Honey plorts sell superbly for 45 newbucks each in the plort market. Boom plorts fetch 28 newbucks but harvesting non-largo booms can be dangerous!

As a honey boom, feeding them meat, fruit, or veggies yields a generous helping of both valuable plort types. Use auto-collectors to safely gather their plorts and say farewell to random explosions!

A tip for these guys – use air net corridor ceilings so even if agitated, their launched plorts won‘t escape!

Diet: Meat & Produce
Plort Profit: 70 newbucks for 2 (Very High)
Ranching Difficulty: Medium

#7 – Quantum Tangle Largo

This brain-bending duo merges the reality-phasing quantum slime with the ever-escaping tangle slime. Both display teleportation abilities making containment a puzzle to solve!

Tangles produce exceptionally valuable plorts at 75 newbucks a pop in the plort market. Quantums fetch 40 newbucks each which is still well above average.

Once you construct a properly secured corral from tangle-proof fences and air nets, the quantum tangle largo becomes a lucrative opportunity. Their diet of fruit, veggies, and chickens means automated farming and coops will keep profits teleporting skyward!

Pro tip: Use drone collecting since ranchers cannot safely enter quantum tangle enclosures! Also plant cubeberries outside their corral for a favorite snack.

Diet: Fruit & Meat
Plort Profit: 115 newbucks for 2 (Extremely High!)
Ranching Difficulty: Hard

#6 – Crystal Boom Largo

This gorgeous but occasionally sharp largo fuses the gemstone-like crystal slime with everyone‘s favorite walking explosive in the boom slime.

Crystal plorts dazzle as much as real jewels and fetch 60 newbucks apiece on the ranch exchange. Booms produce a very consistent 28 newbucks per plort harvested.

The cool-headed crystals keep those booms calm while still allowing a diet of meat, fruit, and veggies. The launched plorts can poke you so be cautious!

Using blast shields, air nets, auto-collectors and keeping them well-fed minimizes risk while allowing these pretties to finance your entire operation!

One last tip – decorate their corrals with diamonds and slime toys to really make your crystal boom largos shine. Ka-ching! 💎

Diet: Meat & Produce
Plort Profit: 88 newbucks for 2 (Very High)
Ranching Difficulty: Medium

#5 – Hunter Saber Largo

This fierce and flashy largo merges the rugged hunter slime with the sturdy saber slime. Both produce highly valued plorts on the market!

Hunters fetch 60 newbucks per plort which sits near the top end of plort value charts. Meanwhile sabers clock in at 50 newbucks each, still well above average.

Feeding them meat like chickens yields stacks of profitable plorts! The hunter saber largo stays nourished with couple coops nearby while retaining a less aggressive temperament.

Make sure to give them toys though as bored hunter saber largos can still wreck stuff! Construct sturdy steel corrals and use air nets to reduce escaped plorts.

Diet: Meat (Especially Chickens!)
Plort Profit: 110 newbucks for 2 (Extremely High)
Ranching Difficulty: Medium – Hard

#4 – Dervish Mosaic Largo

If your ranch needs more excitement, try producing the intense dervish mosaic largo!

Mosaic slimes crackle with electrical energy, zapping anything nearby. Their plorts bank a modest 32 newbucks each though.

Dervish slimes spin rapidly like tornadoes, flinging debris in their path. Ranchers consider their plorts quite valuable at 50 newbucks a piece!

Fusing these volatile slimes creates a true spectacle – use blast shields to enjoy the show! Feed them vegetables and marvel at the lightshow while profits roll in.

Some tips for success – use air net ceilings and floors for max containment. Set up auto-harvesters since trying to manually collect plorts mid-lightshow seems… unsafe. And as always – avoid agitating them!

Diet: Vegetables
Plort Profit: 82 newbucks for 2 (Very High)
Ranching Difficulty: Hard

#3 – Rad Saber Largo

This radioactive ranch resident combines the hardy saber slime with the hazardous rad slime. Talk about a profitable atomic duo!

Saber plorts trade at 60 newbucks each, rivaling the price of hunter plorts. Rad plorts energize at 52 newbucks a piece!

The rad saber largo feeds itself by absorbing the rads‘ favorite food – the radioactive goo in The Wilds areas! No need to ranch chickens.

Using blast shields, rad scrubs, and lots of auto-harvesters lets these beasts enrich your ranch. Just don‘t cuddle them!

A few tips – plant oca oca outside their corral since rads adore that fruit. Make sure to decontaminate after exposure and equip a rad suit when maintaining their area!

Diet: Radioactive Goo & Oca Oca
Plort Profit: 112 newbucks for 2 (Extremely High!!)
Ranching Difficulty: Hard

#2 – Quantum Saber Largo

For the ultimate end-game largo that will finance an entire Ogden Ortiz-themed ranch, say hello to the quantum saber largo!

We already mentioned quantum plorts sell for 40 newbucks each – quite profitable! And saber plorts claim an impressive 60 newbucks a piece!

This teleporting titan inherits strong saber slime traits to offset the tricky containment needs of quantums. Feeding them phase lemons or chickens via quantum drills yields bucketloads of valuable plorts!

You read that right…quantum drills! To properly manage these reality-bending beasts, your entire ranch needs upgrading to handle their phasing abilities.

Once you construct quantum teleportation-proof enclosures and set up quantum resource extractors for automated food, you‘ll be leaping quantum saber largo returns all the way to the bank! 🏦

Diet: Phase Lemons & Meat
Plort Profit: 100 newbucks for 2 (Extremely High!!)
Ranching Difficulty: Very Hard

#1 – Tangle Boom Largo

Occupying the coveted spot for #1 Best Largo in Slime Rancher 2 is the tangle boom largo!

As mentioned earlier, tangle plorts sell for a staggering 75 newbucks each – the highest in the game! Booms pitch in a consistent 28 newbucks per plort.

The challenge with tangles is their ability to phase through solid objects. But when fused with a boom slime, the tangle boom largo is much easier to properly contain compared to a pure tangle.

Feed them chickens and watch literal money grow on trees! Ensure your corrals have air net ceilings and floors to prevent any escape. Like many advanced largos, lean on drones to automatically extract their plorts.

The profit potential from this amazing largo is nearly unrivaled. Once you solve the containment equation, your tangle boom returns will have you taking Money Baths in no time! 🛀💸

Diet: Meat like chickens
Plort Profit: 103 newbucks for 2 (Extremely High!!)
Ranching Difficulty: Hard

Blueprint for Largo Success

Hopefully this guide has shown the limitless potential two slimes can unlock together as largos. The key is balancing plort value, ease of care, and containment strategy.

Here is the blueprint I use when designing a high-profit slime operation:

Early Game

  • Pink Rock Largos
  • Tabby Phosphor Largos
  • Pink Boom Largos

Mid Game

  • Honey Boom Largos
  • Honey Hunter Largos
  • Quantum Tangle Largos

End Game

  • Tangle Boom Largos
  • Quantum Saber Largos
  • Dervish Mosaic Largos
  • Rad Saber Largos

Start small using common slimes while accumulating newbucks, resources, and access to advanced areas. Once your research tree unlocks the tech to safely manage trickier species, transition to more valuable largos.

Patience pays off immensely! Before you know it, you‘ll go from rookie rancher to Slime Master profiting big off intricate largo operations.

For all newcomers reading this, I hope my decade of Slime Rancher wisdom helps you discover the perfect largos to submerge your ranching dreams in oodles of plorts and newbucks! 😁

Let me know which largos become your favorite or if you discover any other lucrative combos out there!

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